Subtotal: R4 650,00
HDL MOTC 10
R900,00
MOTS-c is a mitochondrial-derived peptide described as a bioactive 16 amino acid peptide. This peptide is detected in circulation, so it is classified as a mitochondrial or metabolic hormone.
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Description
MOTS-c is a mitochondrial-derived peptide described as a bioactive 16 amino acid peptide. This peptide is detected in circulation, so it is classified as a mitochondrial or metabolic hormone. It primarily targets fat and skeletal muscle.MOTS-c is a peptide encoded by the short open reading frame of the mitochondrial 12S rRNA gene. It is significantly expressed in response to stress or exercise and translocated to the nucleus, where it regulates the expression of stress adaptation-related genes with antioxidant response elements (ARE). MOTS-c mainly acts through the Folate-AICAR-AMPK pathway, thereby influencing energy metabolism, insulin resistance, inflammatory response, exercise, aging and aging-related pathologies. Because of the potential role of MOTS-c in maintaining energy and stress homeostasis to promote healthy aging, especially in view of the increasing aging of the global population, it is highly pertinent to summarize the relevant studies. This review summarizes the retrograde signaling of MOTS-c toward the nucleus, the regulation of energy metabolism, stress homeostasis, and aging-related pathological processes, as well as the underlying molecular mechanisms.
Additional information
| Colour | Emerald Green, Royal Blue, Burnt Orange, Turquoise Teal, Mustard Yellow |
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Quick Comparison
| HDL MOTC 10 remove | NOVA Fat Away remove | BP Tirze 60 remove | HDL Tirse 44 remove | NOVA Easy Sleep remove | BP BPC157 & TB500 remove | |||||||||||||
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| Name | HDL MOTC 10 remove | NOVA Fat Away remove | BP Tirze 60 remove | HDL Tirse 44 remove | NOVA Easy Sleep remove | BP BPC157 & TB500 remove | ||||||||||||
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| SKU | IN_LK-42 | IN_LK-18 | IN_LK-7 | IN_LK-12 | IN_LK-17 | IN_LK | ||||||||||||
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| Price | R900,00 | R1 300,00 | R3 800,00 | R2 300,00 | R1 100,00 | R2 200,00 | ||||||||||||
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| Description | MOTS-c is a mitochondrial-derived peptide described as a bioactive 16 amino acid peptide. This peptide is detected in circulation, so it is classified as a mitochondrial or metabolic hormone. | Supports fat metabolism and body composition by targeting stubborn fat while preserving lean muscle. | Tirzepatide is a medication that has gained significant attention for its role in weight loss and managing metabolic conditions like type 2 diabetes. It works by mimicking two natural hormones in the body: glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1). These hormones help regulate blood sugar, control appetite, and support metabolic health. | HD Labs Tirsema 44mg Pen combines two of the most effective weight-loss peptides available — 40mg of Tirzepatide and 4mg of Semaglutide — into one advanced weekly injection. | Supports natural sleep, deeper rest, and recovery with DSIP to promote restorative sleep without sedatives. | This blend combines two well-studied regenerative peptides: BPC-157 (Body Protection Compound-157), a pentadecapeptide derived from human gastric juice with cytoprotective and wound-healing properties[1][2], and TB-500 (Thymosin Beta-4 fragment), a 43-amino-acid peptide involved in tissue repair, cell migration, and angiogenesis[3][4]. | ||||||||||||
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